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Steffen Platschek, Institute of Clinical Neuroanatomy, Goethe University Frankfurt


Use of biophysically realistic models in neuroscience


Owheo G34 - 1:00 pm, Friday 02 October


The brain with its mechanisms remains one of the major unsolved puzzles in science. Synaptic transmission, synaptic plasticity, neuronal connections and arborisation of the dendritic trees are only some of the features of the elementary functional units of the brain, the neurons. Although neuroscience experiments can determine multitude of single features of neurons, compensatory effects in response to experimental manipulation cannot be excluded. Furthermore, investigations of many research questions may not be feasible experimentally. In this talk, biophysically realistic models of the mammalian neuron are introduced that (1) provide full control over all parameters and (2) enable complex simulations. I will show simulations investigating excitability, electrotonic structures and synaptic and morphological plasticity in neurons.

Last modified: Tuesday, 29-Sep-2015 16:36:40 NZDT

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